分类目录归档:学术报告

学术报告分类。如果是学术报告请勾选此分类

5月18日 Jaladhar Neelavalli: Quantitative MR imaging in-utero: Challenges and Opportunities

讲座题目:Quantitative MR imaging in-utero: Challenges and Opportunities

主讲人: Jaladhar Neelavalli

主持人: Yang Guang

开始时间: 2016-05-18 14:30

讲座地址: 理科大楼A228

报告人简介
Jaladhar Neelavalli has been focusing on developing methods to improve quantitative susceptibility mapping (QSM/SWIM) and post processing methods for susceptibility weighted imaging (SWI). Specifically, he is interested in developing these methods for quantification of venous oxygen-saturation changes in normal versus abnormal clinical conditions. He is now modifying and applying these methodologies to fetal MR imaging with a view to study what changes in the vascular development and oxygen utilization in the developing brain in-utero in normal versus high-risk pregnancies. Dr. Neelavalli has a strong background in MR physics and fetal imaging.

报告简介
Fetal growth restriction occurs in 16% of pregnancies worldwide where insufficient nutrient supply along with hypoxemia is often implicated. The condition is associated with both short and longterm neurological sequelae. MR imaging is an excellent tool for quantitative imaging that can help us better understand the in-vivo physiology. This talk would discuss the technical challenges in quantitative MR imaging of the human fetus with specific focus on blood-oximetry, phase contrast imaging and MR angiography. Some of the recent approaches attempting to address these issues and the quantitative results from these methods will be presented.

5月18日 Liu Saifeng: Quantification of liver iron concentration using the apparent susceptibility of the vessels.

讲座题目:Quantification of liver iron concentration using the apparent susceptibility of the vessels.

主讲人: Liu Saifeng

主持人: Yang Guang

开始时间: 2016-05-18 13:00

讲座地址: 理科大楼A228

报告简介:

Liver iron concentration (LIC) quantification is indispensable for the diagnosis and monitoring of treatment for patients undergoing chronic blood transfusion. Although the LIC can be measured using R2 and R2* methods, the accuracy and precision is still limited, especially for high iron concentration. Quantitative susceptibility mapping (QSM) has been shown to be effective in quantifying cerebral iron content. In this study, we show a method which extends QSM from the brain to the liver. Specifically, we quantify the iron concentration in the liver tissue by measuring the apparent susceptibility of the vessels in the liver. Simulation, phantom and in vivo studies show that much higher accuracy and precision in measuring LIC can be achieved.

4月5日 马培翔:From atoms to invisible states: probing protein conformation with NMR

讲座题目:From atoms to invisible states: probing protein conformation with NMR
主讲人: 马培翔
主持人: 姚叶峰
开始时间: 2016-04-05 09:30
讲座地址: 理科大楼A510

报告人简介:

2007年获得德国政府Helmholtz-DAAD奖学金资助赴德国攻读于利希研究中心(Forschungzentrum Juelich)的联合博士学位。在于利希研究中心学习工作期间,科研工作的主要内容是以自噬为研究对象,结合生物物理, 生物化学的方法,利用核磁共振技术,研究蛋白质相互作用的作用位点和构象转化。首次将纳米磷脂盘技术应用到膜锚定蛋白质的构象转化研究中,解决了磁共振系统中膜蛋白不稳定的难题。博士毕业后加入法国科学院的结构生物学研究所进行博士后研究。期间利用稳定同位素标记技术和磁共振中的弛豫现象研究生物大分子的隐态构象,首次在实验中验证了蛋白质晶体的振动,受到了行业内广泛好评,多次受邀在国际会议做报告。在Angew Chem Int EdEngl,Autophagy,Nature communication等发表十余篇文章,引用百余次。

12月25日 郭华:多次激发高分辨扩散成像和其临床应用

讲座题目:多次激发高分辨扩散成像和其临床应用
主讲人: 郭华
主持人:
开始时间: 2015-12-25 14:00
讲座地址: 理科大楼A228

报告人简介:

郭华,清华大学医学院生物医学影像研究中心研究员,博士生导师。2006毕业于美国杜克大学生物医学工程系,曾在Siemens公司,香港大学和美国纽约大学进行磁共振成像的研究工作。在2010年加盟清华大学前曾任美国纽约大学放射系助理教授。在核磁共振领域有超过10年的研究经验,熟悉三大磁共振系统(GE、Siemens和Philips)上的序列开发。研究兴趣主要包括:磁共振物理,包括新序列设计、图像重建、对比机制研究,希望通过技术的改进来提供大信息量的高时空分辨率、多参数的定量影像或功能成像;其次是这些基本技术的临床和研究应用,特别地,感兴趣开发、优化和评估可用于慢性肝病的新的磁共振技术,进而可以提高肝病的早期诊断、治疗监测及探究背后发病的生理和病理机制。在JMRI, MRM, Neuroimage等国际高水平杂志发表论文数十篇。

11月18日 高红昌: 磁共振波谱研究糖尿病脑病等神经系统疾病的脑代谢机制

讲座题目:磁共振波谱研究糖尿病脑病等神经系统疾病的脑代谢机制
主讲人: 高红昌
主持人: 杜小霞
开始时间: 2015-11-18 13:00
讲座地址: 理科大楼A510

报告人简介:

高红昌博士是温州医科大学分析测试中心实验室主任,学科带头人,教授/博导。2001年7月毕业于华中科技大学,获理学和管理学双学士学位;2006年7月毕业于中国科学院武汉物理与数学研究所,波谱与原子分子物理国家重点实验室,获核磁共振波谱学博士学位。2006年进入中科院上海药物研究所从事博士后研究,出站评为副研究员;同年,作为高层次人才引进到温州医科大学药学院从事教学科研工作,并主持建设温州医科大学600MHz核磁共振实验室和代谢组学与医药核磁共振研究所。2012年晋升教授,博士生导师。入选浙江省医坛新秀卫生高层次人才,浙江省新世纪151人才,温州市新世纪551人才和中青年学科带头人。是《高等学校化学学报》、《波谱学杂志》、《化学学报》,和国外diabetes, obesity and Metabolism, Hepatology, Journal of Biomolecular NMR, 和Molecular Nutrition & Food Research等杂志的特邀审稿专家。 一直从事核磁共振技术及其在化学和生物医学等方面的应用研究,主持完成了国家自然科学基金、中国博士后科学基金等国家级和省市级项目研究。至今已发表SCI收录论文40余篇,其中多篇在Metabolomics, Molecular Neurobiology, Journal of Proteome Research, Molecular BioSystems等期刊发表。获得浙江省科技进步二等奖,浙江省卫生厅科技二等奖,温州市科技进步二等奖等科技成果。

报告简介:

代谢组学是继基因组学、转录组学和蛋白质组学之后在科学界新发展起来的学科,通过评价组织和其他生物体液中内源代谢物的变化情况来反应疾病或者治疗状况。1H NMR的代谢组学方法可以利用生物体内小分子代谢物的丰富信息,研究它们所揭示的生物学意义,反映机体在内外因素的影响下整体代谢的变化规律。对于糖尿病的机理研究及临床治疗非常有必要。糖尿病(DM)是一种常见的代谢性疾病,以慢性高血糖、伴随因胰岛分泌不足或作用缺乏引起的糖、脂肪和蛋白质代谢紊乱为特点。高教授报告的主要内容是介绍磁共振波谱研究糖尿病脑病等神经系统疾病的脑代谢机制,探讨糖尿病引起的代谢紊乱如何导致中枢神经系统和泌尿系统并发症的发病机制等问题。

8月12日 Hongyu An:Quantitative Cerebral Oxygen Metabolism and its application in stroke Simultaneous PET/MR imaging: challenges, opportunities and applications(物理学系列学术报告)

讲座题目:Quantitative Cerebral Oxygen Metabolism and its application in stroke Simultaneous PET/MR imaging: challenges, opportunities and applications
主讲人: Hongyu An
开始时间: 2015-08-12 9:00
讲座地址: 理科大楼A510

报告人简介:

Dr. Hongyu An is an assistant professor in the department of Radiology, and Biomedical Research Imaging Center (BRIC) at University of North Carolina at Chapel Hill, and also the MR modality leader in the BRIC at UNC. He has extensive experience in MR oxygen metabolic imaging, perfusion (Dynamic Susceptibility Contrast and Arterial Spin Labeling) imaging, susceptibility weighted imaging (SWI), diffusion tensor imaging (DTI), phase contrast imaging, MR spectroscopy, quantitative T1 and T2 measurements, and attenuation and motion correction for simultaneous PET/MR measurements. He is the PI and a co-investigator on numerous NIH, foundation and industry grants. I have published 53 peer reviewed full journal papers, two book chapters, eight full conference papers and over 130 conference abstracts.

报告简介:

Elevation of oxygen extraction fraction (OEF) in brain tissue portends a 6-7 fold increased risk of subsequent stroke in patients with chronic atherosclerotic carotid artery occlusion. In this talk, Dr. An will introduce MR methods that we have used to obtain cerebral OEF and MR oxygen metabolic index (MROMI), and will also talk about how we use MROMI to identify ischemic penumbra in stroke patients. Simultaneous PET/MR imaging offers exciting opportunities. Registration of PET and MRI is a natural consequence of the PET/MR scanner. The simultaneity of PET and MR on these devices is the key to realizing their potential. However, one major challenge of simultaneous PET/MR imaging is attenuation correction (AC). Dr. An will talk about some novel methods that we have developed to do MR based AC for PET and will introduce a novel MR method to obtain motion information.

8月3日 葛玉林:7T Susceptibility MRI of human brain Gas-enhanced brain MRI: methodology & its clinical applications Seeing is believing: the role of MRI in multiple sclerosis(物理系校级学术报告)

讲座题目:7T Susceptibility MRI of human brain Gas-enhanced brain MRI: methodology & its clinical applications Seeing is believing: the role of MRI in multiple sclerosis
主讲人: 葛玉林
开始时间: 2015-08-03 9:00
讲座地址: 理科大楼A510

报告人简介:

葛玉林教授系纽约大学医学院放射系教授,主要从事神经影像研究,发表论文 80余篇,被引用达到5337次,研究主要包括:1) 开发尖端可用于临床定量的MRI技术;2) 用这些MRI技术研究多种中枢神经系统退行性疾病包括:多发性硬化,脑外伤,和老年痴呆;3) 超高磁场MRI和脑血管疾病。葛玉林教授曾经多次获得国际各种奖项,并曾担任AJNR等多个影像和神经科的杂志编委以及十几个杂志的审稿人。同时,葛玉林教授是几项由美国国家健康研究院(NIH)资助项目的主要负责人,还是NIH两个基金会的主要评审员。他的影像研究成果在多发性硬化和脑外伤领域内有广泛的影响。

报告简介:

In this talk, strengthens and challenges using whole body human ultra-high-field 7T system will be reviewed; how to establish a MR compatible gas-delivery system and the associated protocol that allow the delivery of special gas mixtures (e.g., O2, CO2, N2, and their combinations); and how to interpret oxygenation-based MRI signals in functional and susceptibility-weighted imaging ; and the contribution of MR imaging in MS will be reviewed and a discussion of several novel hypotheses tested by advanced MR techniques in order to better understand disease pathogenesis, natural history and disease progression will be provided.

4月17日 Yongfeng Hu:Synchrotron radiation light source: introduction and applications in material science (物理学系列学术报告)

讲座题目:Synchrotron radiation light source: introduction and applications in material science
主讲人: Yongfeng Hu
开始时间: 2015-04-17 9:30
讲座地址: 理科大楼A207会议室

报告人简介:

Dr. Yongfeng Hu is the staff scientist at the Canadian Light Source, and he is an adjunct professor at the Department of Chemical Engineering at the University of Saskatchewan. He obtained his Ph.D in Physical Chemistry from University of Western Ontario in 1996. He has over 20 years of experience in beamline operation and construction at several synchrotron facilities in US and Canada. He has been responsible of building and commissioning two beamlines at the Canadian Light Source. His research interest has been centered on the application of synchrotron based techniques in chemistry, physics, material science, and environmental science research. He is theauthor/co-author of about 150 peer-reviewed publications in areas of material and environmental science, atomic and molecular chemistry and physics, and synchrotron instrumentation.

报告简介:

Synchrotron radiation facilities are advancing and becoming more widely available to support fundamental and applied research in almost all domains of science, such as material, life science and environmental research. Synchrotrons produce beams of light in spectrum ranging from infrared to soft and hard X-rays and various beamlines are built to optimize a specific range of light to study various matters. The application of synchrotron is multi- and inter-disciplinary and the information obtained could also be multi-dimensional: be it in the energy scale (the electronic/bonding); in spatial (imaging and microscopy) or in time scale (time resolved). In this presentation, an introduction to the synchrotron radiation and related techniques will be presented. A few research examples specifically in the nano materials, such as battery materials and nano catalytic materials will be given.

4月7日 Daniella Goldfarb:DNP技术以及自由基的动态转移在电子顺磁共振中的应用(物理学系列学术报告)

讲座题目:DNP技术以及自由基的动态转移在电子顺磁共振中的应用
主讲人: Daniella Goldfarb
开始时间: 2015-04-07 09:30
讲座地址: 理科大楼A510会议室

报告人简介:

Professor Daniella Goldfarb,以色列威兹曼科学院化学物理系教授。希伯来大学化学系学士(1976年),罗得岛大学化学系硕士(1978年),以色列威兹曼科学院同位素研究学博士(1984年)。现为以色列威兹曼科学院化学物理系教授,英国皇家化学学会会员,国际磁共振学会(ISMAR)主席。Professor Daniella Goldfarb的研究工作主要致力于通过电子顺磁共振技术(EPR)解决生物物理以及结构生物学的基本问题。Professor Daniella Goldfarb为EPR技术国际最为知名的学者之一,很多工作发表在Angew.Chem,PCCP, microporous and mesoporous materials,journal of magnetic resonance等国际知名学术刊物上。

报告简介:

通过电子顺磁共振技术(EPR)提供顺磁性分子动力学特征、几何学特征以及电子结构信息是近年来的一个科研热点。报告的主要内容包括:1、介绍电子顺磁共振技术(ERP)的特点;2、如何通过动态核偏振方法(DNP)以及自由基的动态转移来弥补核磁共振技术对顺磁性分子的研究渠道。报告中Professor Daniella Goldfarb还将介绍其实验室的一些最新研究结果。

3月20日 宋一桥:Recent Development of Magnetic Resonance: Instrumentation, Physics and Applications

讲座题目:Recent Development of Magnetic Resonance: Instrumentation, Physics and Applications
主讲人: 宋一桥
开始时间: 2015-3-20 13:00
讲座地址: 理科大楼A228会议室

报告人简介:

宋一桥,哈佛医学院和麻省总医院生物医学影像Martions研究中心助理神经科学家,斯坦福大学地球物理顾问教授,斯伦贝谢道尔研究中心流体分析及核磁共振项目经理。中国石油大学地球物理与信息工程学院客座教授,华东师范大学“紫江”讲座教授。《Journal of Magnetic Resonance》编委,《New Journal of Physics》特邀编辑。海外华人磁共振协会主席,美国物理学会会员、美国化学学会会员,担任ENC、ICMRM、MRPM诸多国际会议的执行委员。

报告简介:

In recent years, NMR/MRI has become an import technique for characterization of a variety of porous media including inorganic materials and biological tissues. In particular, NMR/MRI measurement of relaxation and diffusion properties has found applications in petroleum exploration, material sciences, medical imaging, and other fields. This talk will outline the physics of the relaxation and diffusion processes in porous media and the recent MR development including multi-echo techniques, compressed sensing, 2D methods for diffusion and relaxation, in particular to study complex diffusion dynamics in porous media. I will also discuss several applications of these techniques in the study of polymer degradation, molecular composition, porosity in sedimentary rocks, food productions and biological tissues. New ideas of NMR instrument will be presented to include miniaturization of NMR electronics into a silicon chip, and a fully broadband front-end electronics without using the conventional resonant circuit.